Type of relationship | MI or GO | Definition |
---|---|---|
Phosphorylation | MI:0217 | phosphorylation
reaction Reversible reaction that can affect D,C,H,S,T,Y,R residues. |
Phosphorylation | GO:0006468 | protein phosphorylation The process of introducing a phosphate group on to a protein. |
Autophosphorylation | GO:0046777 | protein autophosphorylation The phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein. |
Dephosphorylation | MI:0203 | dephosphorylation reaction Phosphoresidues are cleaved and return D,C,H,S,T,Y or R residues. |
Dephosphorylation | GO:0006470 | protein dephosphorylation The process of removing one or more phosphoric residues from a protein. |
Interaction | MI:0914 | association Molecules that are experimentally shown to be associated potentially by sharing just one interactor. Often associated molecules are co-purified by a pull-down or coimmunoprecipitation and share the same bait molecule. |
Interaction | GO:0005515 | protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
Activation | GO:0044093 | positive regulation of molecular function Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. |
Inactivation | GO:0044092 | negative regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding |
Protein regulation | GO:0065009 | regulation of molecular function Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. |
Gene regulation | GO:0010468 | regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. |
Pathway | MI:0619 | pathway Refers to the metabolic or signalling pathway involving an interaction or a complex. |
Pathway | GO:0008150 | Biological Process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |